Uses of Hyaluronic Acid

Uses of Hyaluronic Acid



How does hyaluronic acid in cosmetic products benefit our skin?


The unique ability to hold so much water makes HA invaluable to our skin. Cosmetic products incorporate HA in order to make skin smoother, plumper, more even-toned and generally more refreshed looking.3


With age, the content of hyaluronic acid in our skin decreases, which contributes to the loss of moisture and elasticity in the skin and the development of wrinkles. This may be resolved by adding HA to cosmetic products. In these products, HA functions as a humectant, which means it draws water to our skin and increases the water content of the epidermis1,2


Hyaluronic acid’s unique moisturising and viscoelastic properties allow to soften our skin and restore its elasticity, thereby an anti-wrinkle effect is achieved.3


What are the benefits of hyaluronic acid-based products?


Besides providing intense hydration, plumping and firming our skin, HA-based products can also improve an uneven skin tone and help treat skin damaged by external factors, such as smoke and ultraviolet (UV) irradiation from the sun.3

This molecule also plays an important role in reducing oxidative damage to the skin due to both internal (the normal ageing process) and external factors.3,4

Furthermore, the newly designed formulations of cross-linked HA mentioned previously, offer noticeable improvements in skin lustre, tone, and texture when added to serums and creams.5,6


1. Olejnik, A., Goscianska, J. and Nowak, I. Significance of hyaluronic acid in cosmetic industry and aesthetic medicine. Chemik 66, 129–135 (2012).

2. Papakonstantinou E, Roth M, Karakiulakis G. Hyaluronic acid: A key molecule in skin aging. Dermatoendocrinol. 2012 Jul 1;4(3):253-8.

3. Brown MB, Jones SA. Hyaluronic acid: a unique topical vehicle for the localized delivery of drugs to the skin. J Eur Acad Dermatol Venereol. 2005 May;19(3):308-18.

4. Mendoza G, Prieto JG, Real R, et al. Antioxidant profile of hyaluronan: physico-chemical features and its role in pathologies. Mini Rev Med Chem. 2009 Nov 1;9(13):1479-88.

5. Sundaram H, Mackiewicz N, Burton E, et al. Pilot Comparative Study of the Topical Action of a Novel, Crosslinked Resilient Hyaluronic Acid on Skin Hydration and Barrier Function in a Dynamic, Three-Dimensional Human Explant Model. J Drugs Dermatol. 2016 Apr;15(4):434-41.

6. Data on File. 3

7. Curinga G and Rusciani A. (2014). Hyaluronic Acid for Facial Rejuvenation. In Minimally Invasive Procedures for Facial Rejuvenation. CA: OMICS Group eBooks

8. Topical report. Injectible products to fill wrinkles. France: ANSM: Agence nationale de sécurité du médicament et des produits de santé; 2012.



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