

Uses of Hyaluronic acid
One of the biggest concerns when it comes to ageing skin is hydration.17 An impaired skin barrier function, increased water loss through the epidermis and decreased water content all characterise ageing skin.22
For this reason, hyaluronic acid, which is well known to counter these defects, is a popular ingredient in many aesthetic and cosmetic products.15,18,23
Thanks to its ability to stimulate collagen production and its excellent capacity to retain water, hyaluronic acid deeply hydrates your skin, giving it the plump, radiant, healthy, youthful glow we all desire.15,23-25

HYALURONIC ACID DERMAL FILLERS
In addition to being able to deeply hydrate the skin, hyaluronic acid dermal fillers have unique features and benefits to:15,16,18,26
- Restore lost volume, plump out the skin and give shape and contour to the face
- Fill lines, creases and wrinkles to restore a fresh, rejuvenated appearance
- Safely and effectively treat skin concerns, with minimal treatment and recovery time (Depending on the corrections to be made and the results sought, one or more treatment sessions may be necessary to obtain an optimal result. This should be determined by the health professional in charge of the treatment.)
- Treatments usually last up from 6 to 24 months (Average duration depends on several factors : patients skin type, severity of the wrinkles/fold to be corrected, type of injection and volume injected.)
Depending on the corrections to be made and the results sought, one or more dermal filler treatment sessions may be necessary to obtain an optimal result.16 This should be determined by the health professional in charge of the treatment.
Whether you are new to hyaluronic acid dermal fillers or are considering exploring different products to help you improve your appearance, click on the link below to learn more about our complete range of hyaluronic acid dermal fillers that offer an immediate rejuvenating and natural beauty effect.27

HYALURONIC ACID INJECTION SYSTEM
The TEOSYAL® Pen*, our hyaluronic acid injection system offers a smoother, more comfortable injection experience for patients while providing practitioners with an easier, more precise injection platform, for even more natural-looking and balanced results.28,29
*TEOSYAL® PEN is a non-sterile device class IIa (CE 0434) intended to assist medical practitioners for dermal filler injections. Manufactured by JuvaPlus in Switzerland. For more information, please consult the user guide of TEOSYAL® PEN or the recommendations available at www.teosyalpen.com. Only a qualified and competent practitioners are allowed to use TEOSYAL® PEN. The use of TEOSYAL® PEN and the results generated are the responsibility of the practitioner. The practitioner is the only one able to evaluate the relative indications and contraindications of the technique to be used, the product to be administered and the needle to be used

COSMETICS
BEFORE AND AFTER AN AESTHETIC TREATMENT
To further help you achieve your desired look, we offer a complete range of cosmeceutical skincare products formulated with a combination of a similar reinforced hyaluronic acid present in our injectable dermal fillers (RHA resilient hyaluronic acid®) and innovative active ingredients for a targeted response to anti-ageing concerns.11
Our hyaluronic acid based cosmetics perfectly complement facial aesthetic procedures and may also be used to prepare and strengthen the skin before the initiation of a professional aesthetic act, or to soothe and protect the skin after.11,30

FOR DAILY USE
While hyaluronic acid-based cosmetic products won’t give you the dramatic, instantaneous results that a hyaluronic acid filler can, combinations of our high quality cosmetics and hyaluronic acid dermal fillers thoroughly and effectively rejuvenate your skin from within, for a healthy, youthful complexion.22,31
See more
15. Olejnik, A., Goscianska, J. and Nowak, I. Significance of hyaluronic acid in cosmetic industry and aesthetic medicine. Chemik 66, 129–135 (2012)
16. TEOXANE Data on File_Recap sheet expert toolbox_500293-01
17. Papakonstantinou E, Roth M, Karakiulakis G. Hyaluronic acid: A key molecule in skin ageing. Dermatoendocrinol. 2012 Jul 1;4(3):253-8
18. Fida M, Dervishi O, Pupo L, Bezati B, Lashi E, Vasili E. Aesthetic dermatology today. Int J Sci Res. 2015;4(10):1799-803
22. Sundaram H, Mackiewicz N, Burton E, et al. Pilot Comparative Study of the Topical Action of a Novel, Crosslinked Resilient Hyaluronic Acid on Skin Hydration and Barrier Function in a Dynamic, Three-Dimensional Human Explant Model. J Drugs Dermatol. 2016 Apr;15(4):434-41
23. Brown MB, Jones SA. Hyaluronic acid: a unique topical vehicle for the localized delivery of drugs to the skin. J Eur Acad Dermatol Venereol. 2005 May;19(3):308-18
24. Fanian F, Jeudy A, Lihoreau T, Moisenier S, Delobel P, Meunier S, Humbert P, In-vivo injection of oligonutrients and high molecular weight hyaluronic acid - results of a randomized controlled trial. Aesthetic Medicine.2017;3(4):23-33
25. Baspeyras M, Rouvrais C, Liégard L, et al. Clinical and biometrological efficacy of a hyaluronic acid-based mesotherapy product: a randomised controlled study. Arch Dermatol Res. 2013 Oct;305(8):673-82
26. Topical report. Injectible products to fill wrinkles. France: ANSM: Agence nationale de sécurité du médicament et des produits de santé; 2012
27. TEOXANE Data on File. TEOSYAL RHA® Brochure_500274-04
28. TEOXANE Data on File_Teosyal Pen_Patient Leaflet_500257-01
29. Kantar Health. The European TEOSYAL®PEN survey included 30 physicians and 236 patients. 42 patients had never received manual injection with a hyaluronic acid-based filler. Report n°40HB64. 2015
30. Use-test under dermatological control on 8 patients after Hyaluronic acid intradermally needle injections performed by an independent laboratory
31. Wisniewski JD, Ellis DL, Lupo MP. Facial rejuvenation: combining cosmeceuticals with cosmetic procedures. Cutis. 2014 Sep;94(3):122-6
